As a neurologist, I’ve always been driven by an evidence-based approach to medicine, but as a woman, I’m deeply attuned to the realities of cyclical health. Lately, both in my clinical practice and within our Two Moons community, I’ve noticed a wave of confusion. With wellness content exploding around Mast Cell Activation Syndrome (MCAS) and histamine 'buckets,' many are left wondering if histamine is the hidden culprit behind their severe PMS. Let’s look at what the research actually says about how our reproductive hormones interact with histamine biology.

I am Dr. Nashat Latib, a functional medicine practitioner specializing in fertility. I spend my days working with women who have been told, in one way or another, that their labs “look normal” (so nothing must be wrong) and yet everything feels wrong. That gap is what pulled me into this work, and it is what keeps me in it. What I have noticed, in patient after patient, is that the menstrual cycle is one of the most underused diagnostic tools in women’s health.

We’re Kerstin Recker and Helen Grimshaw, co-founders of Peli Health. One of us came through an emergency c-section with excruciating pelvic pain and no guidance on what came next. The other started noticing pelvic symptoms during perimenopause and had no idea they were connected to her hormones. Between us, we visited multiple doctors trying to get answers, and heard, more than once, that the solution was to “have a glass of wine and relax.” 

Dear Two Moons Readers, I’m Andrea, founder of The Whiny GYNie, and I’m writing to you as someone who spent decades thinking my body was a personal failure. I was the kid who started out skinny… and then puberty hit and my body took a hard left turn into a shape I didn’t recognize. I became dramatically pear-shaped, so disproportionate that I used to say it looked like two bodies sewn together at the waist. For decades, I assumed the problem was discipline. It wasn’t. It was a condition called lipedema.