Results From Our 3rd Party Clinical Trial

An IRB-approved trial conducted by the Citruslabs Research Team,
October 2025 Immediate Study Report

Clinical Trial Key Findings

Participants reported steadily growing relief across multiple symptom categories, with noticeable improvements by the end of Cycle 2.

87%
said they would continue using the product
80%
would recommend it to others
72%
reported less pre-menstrual or menstrual pain
67%
saw reduced bloating and cramps
62%
experienced clearer skin, more stable mood and better sleep
74%
fewer period-related sick days
The study evaluated the effects of Two Moons Seed Cycling Capsules on PMS-related symptoms and overall menstrual health across two menstrual cycles.Participants reported growing relief over time, with a clear cumulative benefit by the end of Cycle 2.

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The Background

Premenstrual syndrome (PMS) affects the majority of women of reproductive age, often disrupting daily life through symptoms like cramps, mood swings, fatigue, skin changes, and digestive issues. 

In search of a natural, non-pharmaceutical alternative, Two Moons Health developed an organic, natural seed cycling protocol using nutrient-rich, hormone-supportive ingredients. 

The seed cycling protocol includes two capsules: “ZEST” for the first two weeks of the cycle, contains flax and pumpkin seeds and “ZEN” for the second two weeks of the cycle, contains sesame and sunflower seeds, as well as psyllium and low dose chasteberry.

About the Study

Forty (40) women aged 18-45 participated in this open label trial, 39 of whom completed the full two-month course. Participants followed a structured protocol: ZEST from Days 1-14, and ZEN from Days 15-28 of their cycle.*

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*Unlike some other seed cycling or PMS supplement brand studies, which may exclude women in perimenopause, PCOS and endometriosis from participation, Two Moons Health specifically requested that the third-party lab not exclude participants who may be in perimenopause or have PCOS or endometriosis in the study design, for greater inclusivity. We also report results after only 2 cycles/months instead of after 3 cycles/months.
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Real Science. Real Results.

Clinically backed balance + all natural ingredients in a capsule.


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DISCLAIMER: these statements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
U.S. patent pending and international patent application pending