As a neurologist, I’ve always been driven by an evidence-based approach to medicine, but as a woman, I’m deeply attuned to the realities of cyclical health. Lately, both in my clinical practice and within our Two Moons community, I’ve noticed a wave of confusion. With wellness content exploding around Mast Cell Activation Syndrome (MCAS) and histamine 'buckets,' many are left wondering if histamine is the hidden culprit behind their severe PMS. Let’s look at what the research actually says about how our reproductive hormones interact with histamine biology.

As a current Master's in Public Health student focused on nutrition, I find that conversations about hormones come up everywhere - among fellow students, health founders, colleagues, and friends, sometimes in academic settings, sometimes in informal conversations, slowly starting to explore how lifestyle and environment shapes women’s health.

Living with polycystic ovary syndrome (PCOS) can be exhausting. It’s a condition that comes with a constellation of symptoms that can touch many aspects of a woman’s health and life. Disruptions in hormones, insulin and androgen levels can lead to irregular menstrual cycles, acne, hair growth, weight gain, ovarian cysts and, for many women, challenges with fertility.

My name is Mary Bemis, and I’m the founder of Reprise, a line of plant-based and nontoxic activewear. Seven years ago, I discovered that over 90% of my closet was made with plastic. Concerned about the environmental impact of microplastics, I started researching the effects of synthetic fabrics—and what I found was alarming.