As a neurologist, I’ve always been driven by an evidence-based approach to medicine, but as a woman, I’m deeply attuned to the realities of cyclical health. Lately, both in my clinical practice and within our Two Moons community, I’ve noticed a wave of confusion. With wellness content exploding around Mast Cell Activation Syndrome (MCAS) and histamine 'buckets,' many are left wondering if histamine is the hidden culprit behind their severe PMS. Let’s look at what the research actually says about how our reproductive hormones interact with histamine biology.

The luteal phase is where so many women notice changes: in mood, energy, sleep, and cravings, yet it remains one of the least understood parts of the menstrual cycle. In The Period Brain, Dr. Sarah E. Hill sets out to have the luteal phase explained in a way that finally matches women’s experience. In this conversation, she shares why this stage has been historically understudied, what drives common luteal phase mood swings and symptoms, and how everyday habits can either make them worse or help ease the load.

Abigail Wilson is a London-based writer, director, and actor whose work often explores emotional extremes and overlooked realities. We spoke to Abigail about the making of Overdrive, her award-winning short film Overdrive dives deep into the lived experience of PMDD (Premenstrual Dysphoric Disorder), using sound, stunts, and storytelling to express what words alone often can’t.

Dear Two Moons Readers, I’m Justine Carino. In my group practice based in New York and Connecticut, my team and I help individuals, couples, and families reduce anxiety, improve relationships, and build lives that reflect their core values. I also support ambitious women navigating stress and perfectionism through coaching programs and I’ve seen firsthand how hormonal health plays a key role in emotional wellbeing. I’m grateful to share some of that insight with you here today.